Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Candelilla wax United States Pharmacopeia (USP) Reference Standard | 8006-44-8 | MFCD00146289 | 250MG
Candelilla wax United States Pharmacopeia (USP) Reference Standard | 8006-44-8 | MFCD00146289 | 250MG
Medchemexpress LLC Lidocaine impurity 1 | 39084-88-3 | 99.9% | 232.11 | 25 MG
Lidocaine impurity 1 is an impurity of Lidocaine (HY-B0185). It is intended for research use only, and is not sold to patients.
- Information regarding specific features and benefits is not explicitly provided on the product page.
Apexbio Technology LLC Enzastaurin (LY317615) 170364-57-5 100mg
Enzastaurin (LY317615 CAS 170364-57-5) is an orally bioavailable ATP-competitive inhibitor selective for protein kinase C beta (PKC ) a member of the serine-threonine kinase family implicated in tumor growth and progression By inhibiting PKC (IC50 6 nM) enzastaurin decreases phosphorylation and signaling of downstream effectors including ribosomal protein S6 GSK3 and AKT In cellular assays enzastaurin reduces proliferation and induces apoptosis across diverse tumor types (e g colon cancer HCT-116 glioblastoma U87MG) In vivo studies demonstrate antitumor efficacy in xenograft models highlighting its utility for oncology research
Medchemexpress LLC Diclofenac epolamine | 119623-66-4 | 100.0% | 411.32 | 50 MG
Diclofenac epolamine is a non-steroidal anti-inflammatory drug (NSAID) used for relieving arthritis pain, acute pain, osteoarthritis, and actinic keratosis. It demonstrates good skin absorption characteristics without local adverse reactions or allergies.
- Relieves arthritis pain, acute pain, osteoarthritis, and actinic keratosis.
- Demonstrates good skin absorption characteristics.
- Does not cause local adverse reactions or allergies.
- Effective in treating inflammatory conditions.
- Increases partitioning into the skin.
- Enhances and sustains drug transport through the skin.
Medchemexpress LLC TMPyP4 tosylate | 36951-72-1 | 98.0% | 1363.60 | 50 MG
TMPyP4 tosylate (TMP 1363) is identified as a quadruplex-specific ligand. It functions by inhibiting the interaction between G-quadruplexes and IGF-1. This compound also acts as a telomerase inhibitor, which in turn inhibits the proliferation of cancer cells. Furthermore, TMPyP4 tosylate serves as a stabilizer of nucleic acid secondary structure and an acetylcholinesterase inhibitor. It has also demonstrated antiviral activity against SARS-CoV-2.
- Quadruplex-specific ligand.
- Inhibits the interaction between G-quadruplexes and IGF-1.
- Telomerase inhibitor.
- Inhibits cancer cell proliferation.
- Stabilizes nucleic acid secondary structure.
- Acts as an acetylcholinesterase inhibitor.
- Possesses antiviral activity against SARS-CoV-2.
Apexbio Technology LLC Diclazuril 101831-37-2 10mM (in 1mL DMSO)
Diclazuril is a benzeneacetonitrile derivative displaying anticoccidial activity by targeting developmental stages of parasites It inhibits both asexual replication and sexual gametogenesis phases of coccidia thus disrupting the parasite s proliferative and reproductive cycle In pharmacological studies Diclazuril exhibits inhibitory efficacy against various species of Eimeria parasites associated with coccidial infections in vitro and in vivo with reported IC50 values typically ranging from 0 01 to 2 M depending on parasite strain and assay conditions Additionally this compound serves as an investigative tool in experimental models studying acute Toxoplasma gondii infection pathogenesis parasite-host interactions and therapeutic intervention strategies as well as research on protozoal mechanisms in equine protozoal myeloencephalitis (EPM)
Apexbio Technology LLC Ciclopirox 29342-05-0 200mg
Ciclopirox is a synthetic antifungal compound with broad-spectrum activity against dermatophytes yeasts and molds It disrupts fungal membranes and interferes with essential enzymes inhibiting cell growth and replication Ciclopirox also has antibacterial properties against select Gram-positive and Gram-negative bacteria In vitro it demonstrates anti-inflammatory and anticancer activities suggesting its potential in research on fungal infections inflammation and tumorigenesis The compound s inhibitory concentrations (IC50) in antifungal assays typically range from 0 5 to 5 g/mL depending on the target species and conditions Ciclopirox is used to study fungal pathogenicity and develop therapies for dermatopharmacology and oncology
Apexbio Technology LLC Plerixafor 8HCl (AMD3100 8HCl) 155148-31-5 100mg
Plerixafor 8HCl (AMD3100 8HCl) is a selective antagonist of the chemokine receptor CXCR4 functioning through inhibition of CXCL12 (SDF-1)-dependent signaling and chemotactic responses It acts by blocking CXCR4 activation and subsequent intracellular calcium mobilization induced by SDF-1 displaying IC50 values of approximately 27 3 nM (Ca flux) and 51 nM (chemotaxis) respectively Additionally plerixafor disrupts the binding interaction of radiolabeled SDF-1 with CXCR4-expressing cells This compound is commonly employed in biomedical research for studies targeting CXCR4-mediated cellular migration and signaling pathways involved in immunological processes and tumor biology
Apexbio Technology LLC Metoprolol Tartrate 56392-17-7 10mM (in 1mL DMSO)
Metoprolol Tartrate (CAS 56392-17-7) is a selective 1-adrenergic receptor antagonist employed primarily for cardiovascular research purposes By specifically inhibiting 1-adrenergic receptors located predominantly in cardiac tissue it reduces sympathetic influences on heart rate and myocardial contractility Clinical research has indicated that genetic polymorphisms in 1-adrenergic receptors significantly affect individual hypertensive responses to treatment with metoprolol Due to its targeted mode of action and known genetic modulatory effects it is widely utilized in hypertension and cardiovascular pharmacogenomics studies
Apexbio Technology LLC Fluticasone propionate 80474-14-2 50mg
Fluticasone propionate is a synthetic glucocorticoid receptor (GR) agonist with high receptor selectivity and affinity It exerts anti-inflammatory and immunosuppressive actions by interacting with intracellular GR thereby influencing gene expression pathways and downstream cytokine responses This compound has been widely utilized in biomedical research to study inflammatory signaling mechanisms glucocorticoid receptor mediated transcriptional regulation and immune responses associated with asthma allergic rhinitis and related inflammatory diseases Reported in vitro studies demonstrate fluticasone propionate s GR agonist activity with an IC50 value in the subnanomolar range (approximately 0 5 nM) supporting its frequent utilization as a standard GR agonist in receptor-binding assays and inflammation-related experiments
Sigma Aldrich Fine Chemicals Biosciences Glucose monohydrate European Pharmacopoeia (EP) Reference Standard | 14431-43-7 | MFCD00149450 |
Glucose monohydrate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 198.17 | 14431-43-7 | MFCD00149450 |
![Medchemexpress LLC 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxamide | 64372-56-1 | MFCD24857372 | 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000269462.png-250.jpg)
Medchemexpress LLC 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxamide | 64372-56-1 | MFCD24857372 | 10mg
Citalopram impurity-1 (Compound iv) is an amide impurity generated during the synthesis of Citalopram (HY-121203)[1]
![Medchemexpress LLC 2-butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-... | 1026075-53-5 | MFCD23160685 | 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000269439.png-250.jpg)
Medchemexpress LLC 2-butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-... | 1026075-53-5 | MFCD23160685 | 5mg
Timolol impurity 1 is an impurity of Timolol (HY-17494)
Medchemexpress LLC Tolazamide | 1156-19-0 | 99.9% | 50 MG
Tolazamide is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel. It possesses anti-diabetic properties, capable of lowering blood glucose, decreasing insulin dose while maintaining adequate metabolic control, and improving or normalizing hyperglycemia and HbA. This product is intended for research use only and is not sold to patients.
- Inhibits sulfonylurea receptor 1 (SUR1)
- Possesses anti-diabetic properties
- Lowers blood glucose
- Decreases insulin dose while maintaining adequate metabolic control
- Improves or normalizes hyperglycemia and HbA
- For research use only
Medchemexpress LLC Cabozantinib impurity 1 | 918642-61-2 | MFCD16676129 | 50mg
Cabozantinib impurity 1 is an impurity of Cabozantinib (HY-13016)