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Filtered Search Results
Apexbio Technology LLC Salinomycin 53003-10-4 10mg
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Salinomycin is a polyether ionophore antibiotic derived from Streptomyces albus with demonstrated antitumor activities against various cancer cell types It is proposed to function by disrupting multiple signaling pathways including Wnt/ -catenin signaling and interference with ABC drug transport proteins In vitro research on human hepatocellular carcinoma (HCC) cell lines HepG2 SMMC-7721 and BEL-7402 indicates antiproliferative effects with IC50 values of 7 7 M 13 7 M and 10 4 M respectively after 24-hour treatment Studies show that salinomycin induces cell cycle arrest apoptosis via increased Bax/Bcl-2 ratio reduces -catenin expression and elevates intracellular calcium concentrations In vivo assays using orthotopic liver cancer models corroborate its antiproliferative and pro-apoptotic activities suggesting utility in oncology research
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Medchemexpress LLC Cephalexin (Standard) | 15686-71-2 | 99.9% | 1 ML
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Cephalexin is a potent, orally active semisynthetic cephalosporin antibiotic. It has a broad antibacterial spectrum, demonstrating activity against various gram-positive and gram-negative bacteria by targeting penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. This product is for research use only and is not sold to patients.
- Potent, orally active semisynthetic cephalosporin
- Broad antibacterial spectrum
- Demonstrates activity against gram-positive and gram-negative bacteria
- Inhibits bacterial cell wall assembly by targeting penicillin-binding proteins (PBPs)
- 99.91% purity
- Provided as a 10 mM * 1 mL solution in water
- Suitable for research on pneumonia, strep throat, and bacterial endocarditis
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Sigma Aldrich Fine Chemicals Biosciences Choline fenofibrate United50MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Selleck Chemical LLC Atipamezole hydrochloride 10mg 104075-48-1 Antisedan, MPV-1248 hydrochloride, MPV1248 hydrochloride, MPV 1248 hydrochloride
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Atipamezole (Antisedan, MPV1248) is a synthetic ?2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC 3,5-bis(2-cyanoprop-2-yl)benzyl bromide | 120511-84-4 | MFCD07782114 | 5g
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Anastrozole impurity 1 is an impurity of Anastrozole (HY-14274)
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Medchemexpress LLC Apixaban impurity 2 | 2187409-01-2 | 96.7% | 476.53 | C25H28N6O4 | 10 MG
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Apixaban impurity 2 is an analytical reference impurity of the anticoagulant apixaban intended for research and analytical applications. The substance is supplied as a solid reference standard with a reported purity of 96.7% and CAS number 2187409-01-2; a certificate of analysis and safety data sheet are provided for handling and quality information.
- Analytical reference for impurity profiling and method development.
- Reported purity 96.7% suitable for use as a standard.
- Supplied with COA and SDS for lot-specific data and safe handling.
- Available in small analytical sizes, including 10 MG, to support laboratory testing.
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Apexbio Technology LLC Atazanavir 198904-31-3 10mM (in 1mL DMSO)
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Atazanavir (CAS 198904-31-3) is a small-molecule inhibitor targeting HIV-1 protease It is designed to block protease-mediated cleavage of viral gag and gag-pol polyproteins thereby preventing the maturation of infectious viral particles Atazanavir exerts its biological activity primarily through direct binding to the active site of HIV-1 protease inhibiting polyprotein cleavage In in vitro studies atazanavir demonstrates inhibition of HIV-1 replication with reported EC50 values ranging from 2 6 to 5 3 nmol/L and a protease-inhibition constant (Ki) of approximately 66 nmol/L Based on these pharmacological properties atazanavir holds research potential in anti-retroviral assays and studies involving HIV drug resistance and protease inhibition profiling
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eMolecules 65-45-2 | 2-Hydroxybenzamide | Oakwood Chemical137.138 | C7H7NO2 | 99.000 | NC(=O)c1ccccc1O | 1g | 537701996
2-Hydroxybenzamide | Oakwood Chemical | 65-45-2137.138 | C7H7NO2 | 99.000 | NC(=O)c1ccccc1O | 1g | 537701996
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Apexbio Technology LLC Econazole nitrate 24169-02-6 5g
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Econazole nitrate (24169-02-6) is a small-molecule inhibitor targeting the enzyme 14 -demethylase It is designed to disrupt ergosterol synthesis in fungal membrane sterol biosynthesis thereby decreasing membrane integrity altering permeability and attenuating fungal cellular growth Econazole nitrate exerts its biological activity primarily through inhibition of 14 -demethylase In vitro studies demonstrate antifungal activity with reported IC50 values against various fungal isolates typically ranging from approximately 0 05 to 1 g/mL depending on experimental parameters and organism specificity Based on these pharmacological properties econazole nitrate holds research potential in antifungal susceptibility testing exploration of drug resistance mechanisms in fungal strains characterization of dermatopathogenic microorganisms and drug target identification studies
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Medchemexpress LLC Rebamipide impurity 13 | 4876-17-9 | MFCD22194962 | >=98.0% | 193.63 | C10H8ClNO | 100 MG
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Rebamipide impurity 13 is a defined impurity of the gastroprotective agent rebamipide supplied for research and analytical use. It is intended as a reference standard, impurity profiling aid, or synthetic intermediate for drug-development and analytical chemistry. Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Defined chemical impurity for analytical standards.
- Suitable for impurity profiling and method development.
- Useful as a synthetic intermediate for organic synthesis.
- Molecular formula C10H8ClNO; molecular weight 193.63.
- Store as powder or in solvent per recommended conditions.
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Selleck Chemical LLC Lenalidomide S1029-1g
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Lenalidomide is a TNF- secretion inhibitor with IC50 of 13 nM in PBMCs Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) and it causes selective ubiquitination and degradation of two lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis
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Apexbio Technology LLC Betahistine 2HCl 5579-84-0 10g
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Betahistine 2HCl (CAS 5579-84-0) is a small-molecule inhibitor targeting histamine H3 receptors exhibiting an inhibitory concentration (IC50) of 1 9 M By antagonizing H3 receptors betahistine modulates histaminergic neurotransmission which influences the release of various neurotransmitters in the central nervous system This compound is widely utilized in research focused on the physiological roles of histamine signaling particularly in studies of neurological and vestibular disorders as well as in the exploration of H3 receptor pharmacology and modulation
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Med Vet International Miltex Frazier Suction Tube, 7in, 10 French, Angled, Mh19-575
The number one disinfecting wipe in healthcare. Effective against 30 microorganisms in 2 minutes. Fast contact time allows for a quick room turnover. Ideal for daily use in fast-paced environments that require short contact times and broad coverage of microorganisms. Box contains 50 individually wrapped, x-large wipes Convenient for staff to carry or place with specific equipment EPA-registered intermediate level disinfectant Thick, strong wipe has high fluid capacity and is pliable to get into crevices and corners of equipment Pre-moistened wipes are ready to use30 microorganisms, including 6 multi-drug resistant organisms (MDROs)Compatible with a broad range of surfaces and equipment in healthcare Meets CDC, OSHA and CMS Tag F441 guidelines Deep well lid provides ample space to store and access next wipe Prominent contact time for easy identification and improved compliance with accrediation standards.
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Medchemexpress LLC Methanesulfonamide, n-methyl-n-[5-(bromomethyl)-4-(4-fluorophenyl)-2-pyrimidinyl] | 799842-07-2 | MFCD08694308 | 5g
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Rosuvastatin impurity 54 is an impurity of Rosuvastatin (HY-17504A)
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Med Vet International Levofloxacin Tablets (levaquin) 750mg 20ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Levofloxacin Tablets (levaquin) 750mg 20ct
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